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- Table of Contents
Facts about 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial.
| Human | |
|---|---|
| Gene Name: | GCAT |
| Uniprot: | O75600 |
| Entrez: | 23464 |

| Belongs to: |
|---|
| class-II pyridoxal-phosphate-dependent aminotransferase family |

2-amino-3-ketobutyrate-CoA ligase; AKB ligase; Aminoacetone synthase; EC 2.3.1; EC 2.3.1.29; Glycine acetyltransferase; glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); glycine C-acetyltransferase; KBL2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; MGC23053
Mass (kDA):
45.285 kDA

| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (37807894..37817177) |
Strongly expressed in heart, brain, liver and pancreas. Also found in lung.
Mitochondrion. Nucleus. Translocates to the nucleus upon cold and osmotic stress.




PMID: 10712613 by Edgar A.J., et al. Molecular cloning of the human and murine 2-amino-3-ketobutyrate coenzyme A ligase cDNAs.
PMID: 17688197 by Hoshino A., et al. Nuclear translocation of 2-amino-3-ketobutyrate coenzyme A ligase by cold and osmotic stress.