Histone H1oo Antibodies

AND H1FOO ELISA kits, Histone H1oo Proteins

Many biological assays use antibodies to detect Histone H1oo, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H1oo in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H1oo antibodies...

We validate the specificity of these antibodies to Histone H1oo by testing them on tissues known to express H1FOO positively and negatively. Browse below to find the H1FOO antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H1FOO Infographic by Boster Bio

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Anti-Acetylated Histone H1 (Lys25) H1FOO Antibody

1 Q&As

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Histone H1 (Acetyl-Lys25) Antibody

Western blot analysis of lysates from COS7 cells, treated with TSA 400nM 24h, using Histone H1 (Acetyl-Lys25) Antibody

Human, Monkey

ELISA, IF, IHC, ICC, WB

$335
Cat # P12111
100ul

H1FOO Overview

Facts about Histone H1oo.

H1FOO 3D structure. Source: alphafold

Histone H1oo (H1FOO)

May play an integral role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes.

The somatic type linker histone H1c is quickly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo when compared with H1c may contribute to the rapid replacement and increased instability of the embryonic chromatin structure.

Gene Information

Human
Gene Name:	H1FOO
Uniprot:	Q8IZA3
Entrez:

Family

Belongs to:

histone H1/H5 family

Alternative Names

H1 histone family, member O, oocyte-specific; H1OO; histone H1oo; MGC50807; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1

Molecular Weight

Mass (kDA):
35.813 kDA

Genomic Context


Human

Location:
Sequence:	;

Tissue Specificity

Oocyte-specific.

Subcellular Localizations

Cytoplasm. Nucleus. Chromosome.

Diseases

Infertility
Premature Menopause
Aneuploidy
Female Infertility
Ovarian Failure, Premature

Pathways

Oogenesis
Fertilization
Oocyte Growth
Metaphase
Dna Methylation
Localization
Methylation
Enucleation
Cell Proliferation
Dna Hypomethylation
Regulation Of Chromosome Organization
Oocyte Maturation
Spermatogenesis

Embryo Development
Cell Division
Translation
Chromatin Organization
Chromosome Organization
Chromatin Modification
Pachytene

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H1FOO

References

PMID: 12711322 by Tanaka Y., et al. Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte.