Histone H2B type 1-K Antibodies

AND H2BC12 ELISA kits, Histone H2B type 1-K Proteins

Many biological assays use antibodies to detect Histone H2B type 1-K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2B type 1-K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2B type 1-K antibodies...

We validate the specificity of these antibodies to Histone H2B type 1-K by testing them on tissues known to express H2BC12 positively and negatively. Browse below to find the H2BC12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2BC12 Infographic by Boster Bio

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H2BC12 (NM_080593) Human Over-expression Lysate

Human

$628
Cat # LS085236
20 µg, 100 µg

H2BC12 Overview

Facts about Histone H2B type 1-K.

H2BC12 3D structure. Source: alphafold

Histone H2B type 1-K (H2BC12)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	H2BC12
Uniprot:	O60814
Entrez:	85236

Family

Belongs to:

histone H2B family

Alternative Names

Histone H2B type 1-K

Molecular Weight

Mass (kDA):
13.89 kDA

Genomic Context


Human

Location:	6p22.1
Sequence:	6; NC_000006.12 (27138293..27146858, complement)

Subcellular Localizations

Nucleus. Chromosome.

PTMs

Acetylation
Glycoprotein
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2BC12

References

PMID: 9710638 by Lorain S., et al. Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA.

PMID: 11859126 by Kim H.S., et al. Endotoxin-neutralizing antimicrobial proteins of the human placenta.