Histone H2B type W-T Antibodies

AND H2BFWT ELISA kits, Histone H2B type W-T Proteins

Many biological assays use antibodies to detect Histone H2B type W-T, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2B type W-T in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2B type W-T antibodies...

We validate the specificity of these antibodies to Histone H2B type W-T by testing them on tissues known to express H2BFWT positively and negatively. Browse below to find the H2BFWT antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2BFWT Infographic by Boster Bio

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H2BFWT Overview

Facts about Histone H2B type W-T.

H2BFWT 3D structure. Source: alphafold

Histone H2B type W-T (H2BFWT)

Atypical histone H2B.
Nucleosomes containing it are structurally and dynamically indistinguishable from those comprising conventional H2B.

However, unlike traditional H2B, does not recruit chromosome condensation factors and does not take part in the assembly of mitotic chromosomes. May be important for telomere function.

Gene Information

Human
Gene Name:	H2BFWT
Uniprot:	Q7Z2G1
Entrez:

Family

Belongs to:

histone H2B family

Alternative Names

H2B histone family member W testis-specific; H2B histone family, member W, testis-specific; histone H2B type W-T; MGC148130; MGC148131

Molecular Weight

Mass (kDA):
19.618 kDA

Genomic Context


Human

Location:
Sequence:	;

Tissue Specificity

Testis-specific. Present in sperm cells (at protein level).

Subcellular Localizations

Nucleus membrane. Chromosome.

Diseases

Male Infertility
Infertility
Azoospermia
Oligospermia

Pathways

Chromosome Condensation
Spermatogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2BFWT

References

PMID: 15475252 by Churikov D., et al. Novel human testis-specific histone H2B encoded by the interrupted gene on the X chromosome.

PMID: 16449661 by Boulard M., et al. The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes.