Histone H2A type 1-K Antibodies

AND H2ac15 ELISA kits, Histone H2A type 1-K Proteins

Many biological assays use antibodies to detect Histone H2A type 1-K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 1-K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 1-K antibodies...

We validate the specificity of these antibodies to Histone H2A type 1-K by testing them on tissues known to express H2ac15 positively and negatively. Browse below to find the H2ac15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2ac15 Infographic by Boster Bio

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H2ac15 Overview

Facts about Histone H2A type 1-K.

H2ac15 3D structure. Source: alphafold

Histone H2A type 1-K (H2ac15)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	H2ac15
Uniprot:	Q8CGP7
Entrez:	319169

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A type 1-K

Molecular Weight

Mass (kDA):
14.15 kDA

Genomic Context


Mouse

Location:	13\|13 A3.1
Sequence:	13;

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2ac15

References

PMID: 15525528 by de Napoles M., et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

PMID: 15509584 by Fang J., et al. Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.