Histone H2A-like 1 Antibodies

AND H2al1a ELISA kits, Histone H2A-like 1 Proteins

Many biological assays use antibodies to detect Histone H2A-like 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A-like 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A-like 1 antibodies...

We validate the specificity of these antibodies to Histone H2A-like 1 by testing them on tissues known to express H2al1a positively and negatively. Browse below to find the H2al1a antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2al1a Infographic by Boster Bio

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H2al1a Overview

Facts about Histone H2A-like 1.

H2al1a 3D structure. Source: alphafold

Histone H2A-like 1 (H2al1a)

Atypical histone H2A which can replace conventional H2A in certain nucleosomes and might play a role during spermatogenesis. Nucleosomes compact and wrap DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated by means of a complex set of post- translational modifications of histones, also known as histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	H2al1a
Uniprot:	Q5M8Q2
Entrez:	100042922

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A-like 1

Molecular Weight

Mass (kDA):
12.122 kDA

Genomic Context


Mouse

Location:	X\|X A1.1
Sequence:	X;

Tissue Specificity

Testis-specific.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2al1a

References

PMID: 17261847 by Govin J., et al. Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

PMID: 18703863 by Wu F., et al. Testis-specific histone variants H2AL1/2 rapidly disappear from paternal heterochromatin after fertilization.