Histone H4 Antibodies

AND H4c2 ELISA kits, Histone H4 Proteins

Many biological assays use antibodies to detect Histone H4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H4 antibodies...

We validate the specificity of these antibodies to Histone H4 by testing them on tissues known to express H4c2 positively and negatively. Browse below to find the H4c2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H4c2 Infographic by Boster Bio

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H4C2 (NM_003544) Human Over-expression Lysate

Human

$628
Cat # LS008366
20 µg, 100 µg

H4c2 Overview

Facts about Histone H4.

H4c2 3D structure. Source: alphafold

Histone H4 (H4c2)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Rat
Gene Name:	H4c2
Uniprot:	P62804
Entrez:

Family

Belongs to:

histone H4 family

Alternative Names

Histone H4

Molecular Weight

Mass (kDA):
11.367 kDA

Genomic Context


Rat

Location:
Sequence:	;

Tissue Specificity

OGP is found in serum. A potentially OGP- specific transcript is highly expressed in spleen with lower levels in lung, liver, thymus, spinal chord, pituitary gland, adrenal gland, bone marrow and lymph nodes as well as very low levels in kidney, heart and brain.

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H4c2

References

PMID: 3691674 by Grimes S., et al. A rat histone H4 gene closely associated with the testis-specific H1t gene.

PMID: 2920170 by Wolfe S.A., et al. Comparison of the structural organization and expression of germinal and somatic rat histone H4 genes.