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- Table of Contents
Facts about HAUS augmin-like complex subunit 1.
Human | |
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Gene Name: | HAUS1 |
Uniprot: | Q96CS2 |
Entrez: | 115106 |
Belongs to: |
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HAUS1 family |
CCDC5Enhancer of invasion-cluster; coiled-coil domain containing 5 (spindle associated); FLJ40084; HAUS augmin-like complex subunit 1; HAUS augmin-like complex, subunit 1; HEI-CCoiled-coil domain-containing protein 5; HEICFLJ21094; HsT1461
Mass (kDA):
31.863 kDA
Human | |
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Location: | 18q21.1 |
Sequence: | 18; NC_000018.10 (46104385..46128333) |
Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta.
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Localizes with the spindle poles in mitotic cells. In metaphase, localizes to the mitotic asters and is highly punctate on the microtubule array. During later stages of mitosis, remains on the spindle but is not present at the interzone, and is finally observed at the microtubule bundles proximal to the midbody, clearly excluded from the midbody. In contrast, does not colocalize with the tubulin cytoskeleton in interphase cells. In interphase,
PMID: 15082789 by Einarson M.B., et al. Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis.
PMID: 19427217 by Lawo S., et al. HAUS, the 8-subunit human augmin complex, regulates centrosome and spindle integrity.