Histone deacetylase 11 Antibodies

AND HDAC11 ELISA kits, Histone deacetylase 11 Proteins

Many biological assays use antibodies to detect Histone deacetylase 11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 11 antibodies...

We validate the specificity of these antibodies to Histone deacetylase 11 by testing them on tissues known to express HDAC11 positively and negatively. Browse below to find the HDAC11 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Histone deacetylase 11? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the HDAC11 Western Blot Guide

HDAC11 Infographic by Boster Bio

All HDAC11 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HDAC11 Antibody Picoband®

1 Citations

IHC analysis of HDAC11 using anti-HDAC11 antibody (PB9630)

Western blot analysis of HDAC11 using anti-HDAC11 antibody (PB9630)

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9630
100 μg/vial

Anti-HDAC11/Histone Deacetylase 11 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature

Western blot analysis of HDAC11 expression in (1) Jurkat cell lysate;(2) MCF7 cell lysate

Human

IP, WB

$370
Cat # M06209
100 μl

HDAC11 (NM_024827) Human Over-expression Lysate

HDAC11 Human Over-expression Lysates NM_001136041

Human

$628
Cat # LS079885
20 µg, 100 µg

HDAC11 Overview

Facts about Histone deacetylase 11.

HDAC11 3D structure. Source: alphafold

Histone deacetylase 11 (HDAC11)

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays a significant role in transcriptional regulation, cell cycle progression and developmental events.

Histone deacetylases act via the formation of large multiprotein complexes. .

Gene Information

Human
Gene Name:	HDAC11
Uniprot:	Q96DB2
Entrez:	79885

Family

Belongs to:

histone deacetylase family

Alternative Names

EC 3.5.1.98; FLJ22237; HD11; histone deacetylase 11

Molecular Weight

Mass (kDA):
39.183 kDA

Genomic Context


Human

Location:	3p25.1
Sequence:	3; NC_000003.12 (13478903..13506416)

Tissue Specificity

Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.

Subcellular Localizations

Nucleus. Predominantly nuclear.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Paraganglionic Neoplasm
Lymphoma
Inflammation
Leukemia
Traditional Serrated Adenoma
Autoimmunity
Stomach Neoplasms
Malignant Neoplasm Of Breast
Ataxia
Keratoconjunctivitis Sicca
Carcinoma

Immunologic Deficiency Syndromes
Fibrosis
Tumor Angiogenesis
Myeloid Leukemia
Islet Cell Adenoma
Mammary Neoplasms
Medulloblastoma

Pathways

Chromatin Remodeling
Localization
Pathogenesis
Histone Acetylation
Histone Deacetylation
Cell Proliferation
Cell Development
Dna Replication
Tolerance Induction
Cell Activation
Osteoblast Differentiation
T Cell Activation
Immune Response

Nuclear Export
Cell Cycle
T Cell Proliferation
Oligodendrocyte Development
Insulin Secretion
Methylation
Drug Resistance

PTMs

Acetylation

Deacetylation

Methylation

Research Areas

Breast Cancer
Cancer
Epigenetics

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC11

References

PMID: 11948178 by Gao L., et al. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.