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Histone deacetylase 11 Antibodies
AND HDAC11 ELISA kits, Histone deacetylase 11 Proteins
Many biological assays use antibodies to detect Histone deacetylase 11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 11 antibodies...
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HDAC11 Infographic by Boster Bio
All HDAC11 Products
Product
Figures
Specificity
Applications
Price
Human
IP, WB
$370
Cat # M06209
100 μl
Cat # M06209
100 μl
HDAC11 Overview
Facts about Histone deacetylase 11.
Histone deacetylase 11 (HDAC11)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays a significant role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC11 |
| Uniprot: | Q96DB2 |
| Entrez: | 79885 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
EC 3.5.1.98; FLJ22237; HD11; histone deacetylase 11
Molecular Weight
Mass (kDA):
39.183 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.1 |
| Sequence: | 3; NC_000003.12 (13478903..13506416) |
Tissue Specificity
Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
Subcellular Localizations
Nucleus. Predominantly nuclear.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Paraganglionic Neoplasm
- Lymphoma
- Inflammation
- Leukemia
- Traditional Serrated Adenoma
- Autoimmunity
- Stomach Neoplasms
- Malignant Neoplasm Of Breast
- Ataxia
- Keratoconjunctivitis Sicca
- Carcinoma
Pathways
- Chromatin Remodeling
- Localization
- Pathogenesis
- Histone Acetylation
- Histone Deacetylation
- Cell Proliferation
- Cell Development
- Dna Replication
- Tolerance Induction
- Cell Activation
- Osteoblast Differentiation
- T Cell Activation
- Immune Response
PTMs
- Acetylation
Research Areas
- Breast Cancer
- Cancer
- Epigenetics
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC11
bosterbio.com/bosterbio-gene-info-cards/HDAC11
References
PMID: 11948178 by Gao L., et al. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.