Histone H2A type 1-A Antibodies

AND HIST1H2AA ELISA kits, Histone H2A type 1-A Proteins

Many biological assays use antibodies to detect Histone H2A type 1-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 1-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 1-A antibodies...

We validate the specificity of these antibodies to Histone H2A type 1-A by testing them on tissues known to express HIST1H2AA positively and negatively. Browse below to find the HIST1H2AA antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HIST1H2AA Infographic by Boster Bio

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HIST1H2AA Overview

Facts about Histone H2A type 1-A.

HIST1H2AA 3D structure. Source: alphafold

Histone H2A type 1-A (HIST1H2AA)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	HIST1H2AA
Uniprot:	Q96QV6
Entrez:

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A type 1-A

Molecular Weight

Mass (kDA):
14.234 kDA

Genomic Context


Human

Location:
Sequence:	;

Subcellular Localizations

Nucleus. Chromosome.

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIST1H2AA

References

PMID: 15078818 by Aihara H., et al. Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.

PMID: 15010469 by Zhang Y., et al. Phosphorylation of histone H2A inhibits transcription on chromatin templates.