Histone H2A type 1-N Antibodies

AND Hist1h2an ELISA kits, Histone H2A type 1-N Proteins

Many biological assays use antibodies to detect Histone H2A type 1-N, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 1-N in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 1-N antibodies...

We validate the specificity of these antibodies to Histone H2A type 1-N by testing them on tissues known to express Hist1h2an positively and negatively. Browse below to find the Hist1h2an antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hist1h2an Infographic by Boster Bio

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Hist1h2an Overview

Facts about Histone H2A type 1-N.

Hist1h2an 3D structure. Source: alphafold

Histone H2A type 1-N (Hist1h2an)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	Hist1h2an
Uniprot:	C0HKE7
Entrez:

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A type 1-N

Molecular Weight

Mass (kDA):
14.135 kDA

Genomic Context


Mouse

Location:
Sequence:	;

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hist1h2an

References

PMID: 7217105 by Pantazis P., et al. Quantitative determination of histone modification. H2A acetylation and phosphorylation.

PMID: 15525528 by de Napoles M., et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.