Histone H2B type 1-O Antibodies

AND HIST1H2BO ELISA kits, Histone H2B type 1-O Proteins

Many biological assays use antibodies to detect Histone H2B type 1-O, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2B type 1-O in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2B type 1-O antibodies...

We validate the specificity of these antibodies to Histone H2B type 1-O by testing them on tissues known to express HIST1H2BO positively and negatively. Browse below to find the HIST1H2BO antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HIST1H2BO Infographic by Boster Bio

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HIST1H2BO Overview

Facts about Histone H2B type 1-O.

HIST1H2BO 3D structure. Source: alphafold

Histone H2B type 1-O (HIST1H2BO)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	HIST1H2BO
Uniprot:	P23527
Entrez:

Family

Belongs to:

histone H2B family

Alternative Names

Histone H2B type 1-O

Molecular Weight

Mass (kDA):
13.906 kDA

Genomic Context


Human

Location:
Sequence:	;

Subcellular Localizations

Nucleus. Chromosome.

PTMs

Acetylation
Glycoprotein
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIST1H2BO

References

PMID: 1768865 by Dobner T., et al. A novel divergently transcribed human histone H2A/H2B gene pair.

PMID: 16627869 by Beck H.C., et al. Quantitative proteomic analysis of post-translational modifications of human histones.