Histone H2A type 3 Antibodies

AND HIST3H2A ELISA kits, Histone H2A type 3 Proteins

Many biological assays use antibodies to detect Histone H2A type 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2A type 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2A type 3 antibodies...

We validate the specificity of these antibodies to Histone H2A type 3 by testing them on tissues known to express HIST3H2A positively and negatively. Browse below to find the HIST3H2A antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HIST3H2A Infographic by Boster Bio

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HIST3H2A Overview

Facts about Histone H2A type 3.

HIST3H2A 3D structure. Source: alphafold

Histone H2A type 3 (HIST3H2A)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	HIST3H2A
Uniprot:	Q7L7L0
Entrez:

Family

Belongs to:

histone H2A family

Alternative Names

Histone H2A type 3

Molecular Weight

Mass (kDA):
14.121 kDA

Genomic Context


Human

Location:
Sequence:	;

Subcellular Localizations

Nucleus. Chromosome.

Interacting Proteins

UBE2B

PTMs

Acetylation
Citrullination
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIST3H2A

References

PMID: 15078818 by Aihara H., et al. Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.

PMID: 15010469 by Zhang Y., et al. Phosphorylation of histone H2A inhibits transcription on chromatin templates.