HMBOX1 Antibodies

AND HMBOX1 ELISA kits, HMBOX1 Proteins

Many biological assays use antibodies to detect HMBOX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMBOX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMBOX1 antibodies...

We validate the specificity of these antibodies to HMBOX1 by testing them on tissues known to express HMBOX1 positively and negatively. Browse below to find the HMBOX1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMBOX1 Infographic by Boster Bio

All HMBOX1 Products

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Product

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Specificity

Applications

Price

HMBOX1 (NM_024567) Human Over-expression Lysate

HMBOX1 Human Over-expression Lysates NM_001135726

Human

$628
Cat # LS079618
20 µg, 100 µg

Anti-HMBOX1 Antibody

Human, Mouse, Rat

ELISA, IP, WB

$370
Cat # A07353-1
100 μl/vial

HMBOX1 Overview

Facts about Homeobox-containing protein 1.

HMBOX1 3D structure. Source: alphafold

Homeobox-containing protein 1 (HMBOX1)

Transcription element. Isoform 1 acts as a transcriptional repressor.

Isoform 4 has very low activity as a transcriptional repressor. .

Gene Information

Human
Gene Name:	HMBOX1
Uniprot:	Q6NT76
Entrez:	79618

Family

Belongs to:

No superfamily

Alternative Names

FLJ21616; HNF1LA; homeobox containing 1; homeobox-containing protein 1; homeobox-containing protein PBHNF; PBHNF

Molecular Weight

Mass (kDA):
47.278 kDA

Genomic Context


Human

Location:	8p21.1-p12
Sequence:	8; NC_000008.11 (28890394..29064945)

Tissue Specificity

Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, and colon.

Subcellular Localizations

Nucleus. Cytoplasm. Chromosome, telomere. Nucleus, Cajal body. Nucleus, PML body. Predominantly detected in cytoplasm (PubMed:16825764, PubMed:19728927). Localizes in a dynamic manner to actively processed telomeres (PubMed:23685356). Localizes to the periphery of Cajal bodies (PubMed:23685356). Associates with PML nuclear bodies in telomerase-negative cells (PubMed:23813958).; [Isoform 5]: Nucleus. Cytoplasm.

Diseases

Neoplasms
Liver Neoplasms
Lung Injury
Liver Carcinoma
Bronchopulmonary Dysplasia
Infant, Extremely Low Birth Weight
Carcinoma
Immunologic Deficiency Syndromes
Dysplasia

Borderline Personality Disorder
Hiv Infections
Acute Lung Injury

Pathways

Transport
Mrna Splicing
Stem Cell Differentiation
Cell Differentiation
Tube Formation
Nuclear Transport

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMBOX1

References

PMID: 16825764 by Chen S., et al. Isolation and functional analysis of human HMBOX1, a homeobox containing protein with transcriptional repressor activity.

PMID: 19757162 by Zhang M., et al. Characterization of a novel human HMBOX1 splicing variant lacking the homeodomain and with attenuated transcription repressor activity.