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- Table of Contents
HMGA1 Antibodies
AND HMGA1 ELISA kits, HMGA1 Proteins
Many biological assays use antibodies to detect HMGA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGA1 antibodies...
Designing an IHC experiment for HMGA1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HMGA1 IHC GuideHMGA1 Infographic by Boster Bio
All HMGA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01043
100 μl/vial
Cat # M01043
100 μl/vial
HMGA1 Overview
Facts about High mobility group protein HMG-I/HMG-Y.
High mobility group protein HMG-I/HMG-Y (HMGA1)
HMG-I/Y bind preferentially into the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and at the 3'-end processing of mRNA transcripts.
They're also involved in the transcription regulation of genes comprising, or in close proximity to A+T-rich areas. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HMGA1 |
| Uniprot: | P17096 |
| Entrez: | 3159 |
Family
| Belongs to: |
|---|
| HMGA family |
Alternative Names
high mobility group AT-hook 1; High mobility group AT-hook protein 1; High mobility group protein A1; high mobility group protein HMG-I/HMG-Y; High mobility group protein R; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1A; HMG-I(Y); HMGIYMGC12816; HMG-R; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y
Molecular Weight
Mass (kDA):
11.676 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.31 |
| Sequence: | 6; NC_000006.12 (34236873..34246231) |
Subcellular Localizations
Nucleus. Chromosome.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Carcinoma
- Adenocarcinoma
- Diabetes Mellitus
- Tumor Progression
- Mammary Neoplasms
- Diabetes Mellitus, Non-insulin-dependent
- Pancreatic Neoplasm
- Malignant Neoplasm Of Breast
Interacting Proteins
- ORC6
- PRMT6
Pathways
- Cell Growth
- Cell Proliferation
- Cell Cycle
- Pathogenesis
- Rna Interference
- Cell Death
- Chromatin Remodeling
- Dna Repair
- Localization
- Methylation
- Spermatogenesis
- Cell Differentiation
- Senescence
PTMs
- Phosphorylation
- Acetylation
- Methylation
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGA1
bosterbio.com/bosterbio-gene-info-cards/HMGA1
References
PMID: 2505228 by Eckner R., et al. Cloning of cDNAs coding for human HMG I and HMG Y proteins: both are capable of binding to the octamer sequence motif.
PMID: 2701943 by Johnson K.R., et al. Alternative processing of mRNAs encoding mammalian chromosomal high- mobility-group proteins HMG-I and HMG-Y.