HMGCLL1 Antibodies

AND HMGCLL1 ELISA kits, HMGCLL1 Proteins

Many biological assays use antibodies to detect HMGCLL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGCLL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGCLL1 antibodies...

We validate the specificity of these antibodies to HMGCLL1 by testing them on tissues known to express HMGCLL1 positively and negatively. Browse below to find the HMGCLL1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMGCLL1 Infographic by Boster Bio

All HMGCLL1 Products

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HMGCLL1 (NM_001042406) Human Over-expression Lysate

Human

$628
Cat # LS054511
20 µg, 100 µg

HMGCLL1 Overview

Facts about 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic.

HMGCLL1 3D structure. Source: alphafold

3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (HMGCLL1)

Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, an integral step in ketogenesis, the goods of which support energy production in nonhepatic animal cells. .

Gene Information

Human
Gene Name:	HMGCLL1
Uniprot:	Q8TB92
Entrez:	54511

Family

Belongs to:

HMG-CoA lyase family

Alternative Names

3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1; bA418P12.1,3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1; DKFZp434G1411; DKFZP434G1411,3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1; EC 4.1.3.4; probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2

Molecular Weight

Mass (kDA):
39.514 kDA

Genomic Context


Human

Location:	6p12.1
Sequence:	6; NC_000006.12 (55434373..55607573, complement)

Subcellular Localizations

Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.

Diseases

Neoplasms

Pathways

Cellular Localization
Localization

PTMs

Cleavage

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGCLL1

References

PMID: 22865860 by Montgomery C., et al. Identification and characterization of an extramitochondrial human 3- Hydroxy-3-methylglutaryl-CoA lyase.

PMID: 22847177 by Arnedo M., et al. Characterization of a novel HMG-CoA Lyase enzyme with a dual location in endoplasmic reticulum and cytosol.