This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
HMGN1 Antibodies
AND HMGN1 ELISA kits, HMGN1 Proteins
Many biological assays use antibodies to detect HMGN1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGN1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGN1 antibodies...
Designing an IHC experiment for HMGN1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HMGN1 IHC GuideHMGN1 Infographic by Boster Bio
All HMGN1 Products
Product
Figures
Specificity
Applications
Price
HMGN1 Overview
Facts about Non-histone chromosomal protein HMG-14.
Non-histone chromosomal protein HMG-14 (HMGN1)
Binds to the interior side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | HMGN1 |
| Uniprot: | P05114 |
| Entrez: | 3150 |
Family
| Belongs to: |
|---|
| HMGN family |
Alternative Names
FLJ31471; High mobility group nucleosome-binding domain-containing protein 1; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; HMG14; HMG14FLJ27265; HMGN1; MGC104230; MGC117425; non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14
Molecular Weight
Mass (kDA):
10.659 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.2 |
| Sequence: | 21; NC_000021.9 (39342315..39349088, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Genomic Instability
- Neoplasms
- Mammary Neoplasms
- Cytogenetic Abnormality
- Corneal Diseases
- Down Syndrome
- Cell Transformation, Neoplastic
- Cockayne Syndrome
- Neoplasm Metastasis
- Amnesia
Pathways
- Chromatin Remodeling
- Cell Cycle
- Dna Repair
- Transport
- Atp-dependent Chromatin Remodeling
- Immune Response
- Hypersensitivity
- Cell Cycle Arrest
- Nuclear Import
- Mitosis
- Localization
- Embryo Development
- Metaphase
PTMs
- Phosphorylation
- Acetylation
Research Areas
- Apoptosis
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- Checkpoint signaling
- Chromatin Research
- Core ESC-Like Genes
- DNA Double Strand Break Repair
- DNA Repair
- Epigenetics
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGN1
bosterbio.com/bosterbio-gene-info-cards/HMGN1
References
PMID: 3782107 by Landsman D., et al. Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family.
PMID: 2563381 by Landsman D., et al. Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family.