HMGN2 Antibodies

AND HMGN2 ELISA kits, HMGN2 Proteins

Many biological assays use antibodies to detect HMGN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGN2 antibodies...

We validate the specificity of these antibodies to HMGN2 by testing them on tissues known to express HMGN2 positively and negatively. Browse below to find the HMGN2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HMGN2 Infographic by Boster Bio

All HMGN2 Products

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Anti-HMGN2 Antibody Picoband®

13 Q&As

Flow Cytometry analysis of Raji cells using anti-HMGN2 antibody (A04839-2)

Western blot analysis of HMGN2 using anti-HMGN2 antibody (A04839-2)

IHC analysis of HMGN2 using anti-HMGN2 antibody (A04839-2)

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04839-2
100 μg/vial

Anti-Phospho-HMG-17 (S29) HMGN2 Antibody

Immunohistochemical analysis of paraffin-embedded Human brain

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A04839S29
100ul

Anti-HMGN2 Rabbit Monoclonal Antibody

Western blot analysis of HMGN2 expression in K562 cell lysate

Human

IHC, WB

$370
Cat # M04839
100 μl/vial

HMGN2 Overview

Facts about Non-histone chromosomal protein HMG-17.

HMGN2 3D structure. Source: alphafold

Non-histone chromosomal protein HMG-17 (HMGN2)

Binds to the interior side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).

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Gene Information

Human
Gene Name:	HMGN2
Uniprot:	P05204
Entrez:	3151

Family

Belongs to:

HMGN family

Alternative Names

High mobility group nucleosome-binding domain-containing protein 2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; HMG17high mobility group protein N2; MGC5629; MGC88718; non-histone chromosomal protein HMG-17; nonhistone chromosomal protein HMG-17

Molecular Weight

Mass (kDA):
9.393 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (26472440..26476642)

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation.

Diseases

Neoplasms
Malignant Neoplasms
Hepatitis B
Hepatitis
Cell Invasion
Infective Disorder
Cell Transformation, Neoplastic
Pneumonia
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Corneal Diseases
Malignant Neoplasm Of Breast
Alveolar Bone Loss

Carcinoma
Chronic Periodontitis
Mammary Neoplasms
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Suppressor Mutation
Inflammation

Interacting Proteins

TERF2

Pathways

Localization
Chromatin Remodeling
Mitosis
Cell Cycle
Dna Replication
Dna Repair
Metaphase
Atp-dependent Chromatin Remodeling
Methylation
Translation
Interphase
Eye Development
Receptor Transactivation

Hair Follicle Development
Oocyte Maturation
Chondrocyte Differentiation
Embryo Development
Mismatch Repair
Nucleosome Assembly
Fermentation

PTMs

Phosphorylation
Acetylation

Cleavage
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGN2

References

PMID: 3754870 by Landsman D., et al. Chromosomal protein HMG-17. Complete human cDNA sequence and evidence for a multigene family.

PMID: 2565024 by Landsman D., et al. Human non-histone chromosomal protein HMG-17: identification, characterization, chromosome localization and RFLPs of a functional gene from the large multigene family.