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- Table of Contents
HNF1B Antibodies
AND HNF1B ELISA kits, HNF1B Proteins
Many biological assays use antibodies to detect HNF1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNF1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNF1B antibodies...
Designing a Western blot for HNF1B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HNF1B Western Blot GuideHNF1B Infographic by Boster Bio
All HNF1B Products
Product
Figures
Specificity
Applications
Price
HNF1B Overview
Facts about Hepatocyte nuclear factor 1-beta.
Hepatocyte nuclear factor 1-beta (HNF1B)
Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HNF1B |
| Uniprot: | P35680 |
| Entrez: | 6928 |
Family
| Belongs to: |
|---|
| HNF1 homeobox family |
Alternative Names
FJHN; hepatocyte nuclear factor 1-beta; HNF1 beta A; HNF-1 beta; HNF1 homeobox B; HNF1B; HNF-1B; HNF1beta; HNF-1-beta; HNF2; Homeoprotein LFB3; LFB3; LF-B3; MODY5; MODY5HPC11; TCF2; TCF-2; TCF2transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor; Transcription factor 2; transcription factor 2, hepatic; Variant hepatic nuclear factor 1; VHNF1
Molecular Weight
Mass (kDA):
61.324 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (37686431..37745059, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Maturity Onset Diabetes Mellitus In Young
- Liver Carcinoma
- Kidney Diseases
- Diabetes Mellitus, Insulin-dependent
- Cystic Kidney Diseases
- Hyperglycemia
- Neoplasms
- Carcinoma
- Malignant Neoplasms
- Liver Neoplasms
- Insulin Resistance
Pathways
- Secretion
- Insulin Secretion
- Pathogenesis
- Transport
- Glucose Homeostasis
- Regeneration
- Localization
- Cell Differentiation
- Liver Development
- Methylation
- Kidney Development
- Cell Cycle
- Translation
PTMs
- Methylation
- Oxidation
- Phosphorylation
- Reduction
Research Areas
- Diabetes Research
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNF1B
bosterbio.com/bosterbio-gene-info-cards/HNF1B
References
PMID: 1677179 by Bach I., et al. Two members of an HNF1 homeoprotein family are expressed in human liver.
PMID: 7900999 by Bach I., et al. More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing.