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- Table of Contents
HNF4A Antibodies
AND HNF4A ELISA kits, HNF4A Proteins
Many biological assays use antibodies to detect HNF4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNF4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNF4A antibodies...
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HNF4A Infographic by Boster Bio
All HNF4A Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00389
100 μl
Cat # M00389
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1278
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1278
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1720
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1720
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2431
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2431
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00389S313-1
100ul
Cat # A00389S313-1
100ul
Human, Mouse, Rat
IHC, WB
$523
Cat # M00389-1
100 µl
Cat # M00389-1
100 µl
Human, Rat
IHC, WB
$370
Cat # M00389-2
100 μg/vial
Cat # M00389-2
100 μg/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M00389-3
100 μl/vial
Cat # M00389-3
100 μl/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00389-4
100 μl/vial
Cat # M00389-4
100 μl/vial
Human
$960
Cat # LS003172
20 µg, 100 µg
Cat # LS003172
20 µg, 100 µg
HNF4A Overview
Facts about Hepatocyte nuclear factor 4-alpha.
Hepatocyte nuclear factor 4-alpha (HNF4A)
Transcriptionally controlled transcription element. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha.
May be necessary for development of the liver, kidney and gut. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HNF4A |
| Uniprot: | P41235 |
| Entrez: | 3172 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
FLJ39654; hepatic nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4 alpha; HNF-4 alpha; HNF4A; HNF4a7; HNF-4-alpha; HNF4alpha10/11/12; HNF4HNF4a8; MODY; MODY1; NR2A1; NR2A1HNF4a9; NR2A21; Nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; TCF14HNF4alpha; Transcription factor 14; Transcription factor HNF-4; transcription factor-14
Molecular Weight
Mass (kDA):
52.785 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q13.12 |
| Sequence: | 20; NC_000020.11 (44355699..44434596) |
Subcellular Localizations
Nucleus.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Maturity Onset Diabetes Mellitus In Young
- Liver Carcinoma
- Malignant Neoplasms
- Diabetes Mellitus, Insulin-dependent
- Carcinoma
- Hyperglycemia
- Liver Neoplasms
- Neoplasms
- Hyperinsulinism
- Obesity
- Hypoglycemia
Interacting Proteins
- CITED2
- DMD
- EIF1AY
- FOXO6
- NR3C1
- PLPP2
- PPARGC1A
- PROX1
- SFPQ
- SREBF2
Pathways
- Secretion
- Insulin Secretion
- Gluconeogenesis
- Transport
- Hepatocyte Differentiation
- Glucose Homeostasis
- Pathogenesis
- Liver Development
- Cell Differentiation
- Coagulation
- Localization
- Translation
- Cell Cycle
PTMs
- Phosphorylation
- Oxidation
- Acetylation
- Carboxylation
- Methylation
- Ubiquitination
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNF4A
bosterbio.com/bosterbio-gene-info-cards/HNF4A
References
PMID: 8964514 by Kritis A.A., et al. Isolation and characterization of a third isoform of human hepatocyte nuclear factor 4.
PMID: 8622695 by Drewes T., et al. Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes.