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- Table of Contents
HNRNPA1 Antibodies
AND HNRNPA1 ELISA kits, HNRNPA1 Proteins
Many biological assays use antibodies to detect HNRNPA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNRNPA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNRNPA1 antibodies...
Designing a Western blot for HNRNPA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HNRNPA1 Western Blot GuideDesigning an IHC experiment for HNRNPA1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HNRNPA1 IHC GuideHNRNPA1 Infographic by Boster Bio
All HNRNPA1 Products
Product
Figures
Specificity
Applications
Price
Anti-HnRNP A1/HNRNPA1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01476
100 μg/vial
Cat # A01476
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01476
100 μl
Cat # M01476
100 μl
Human
$628
Cat # LS144983
20 µg, 100 µg
Cat # LS144983
20 µg, 100 µg
$1249
Cat # PROTQ32P51
20 µg
Cat # PROTQ32P51
20 µg
HNRNPA1 Overview
Facts about Heterogeneous nuclear ribonucleoprotein A1.
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1)
Involved in the packing of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (PubMed:17371836). May bind to particular miRNA hairpins (PubMed:28431233).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | HNRNPA1 |
| Uniprot: | P09651 |
| Entrez: | 3178 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Helix-destabilizing protein; heterogeneous nuclear ribonucleoprotein A1; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP core protein A1; hnRNPA1; hnRNP-A1; HNRPA1MGC102835; nuclear ribonucleoprotein particle A1 protein; single-strand DNA-binding protein UP1; Single-strand RNA-binding protein
Molecular Weight
Mass (kDA):
38.747 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (54280726..54287087) |
Subcellular Localizations
Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes (PubMed:17289661).; Cytoplasm. (Microbial infection) In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
Diseases
- Malignant Neoplasms
- Neoplasms
- Ataxia
- Muscular Atrophy
- Spinal Muscular Atrophy
- Atrophy
- Nervousness
- Neuromuscular Diseases
- Dental Plaque
- Liver Regeneration Disorder
- Alzheimer's Disease
- Sclerosis
Interacting Proteins
- HNRNPA2B1
- HNRNPA3
- HNRNPC
- HNRNPH3
- KHDRBS1
- PSMD9
- TNPO1
- UBQLN2
Pathways
- Transport
- Localization
- Cell Proliferation
- Pathogenesis
- Mrna Splicing
- Translation
- Nuclear Import
- Mrna Transport
- Methylation
- Rna Interference
- Oxidative Phosphorylation
- Nuclear Export
- Cell Cycle
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPA1
bosterbio.com/bosterbio-gene-info-cards/HNRNPA1
References
PMID: 2760922 by Biamonti G., et al. Isolation of an active gene encoding human hnRNP protein A1. Evidence for alternative splicing.
PMID: 2836799 by Buvoli M., et al. cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms.