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- Table of Contents
HNRNPK Antibodies
AND HNRNPK ELISA kits, HNRNPK Proteins
Many biological assays use antibodies to detect HNRNPK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNRNPK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNRNPK antibodies...
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HNRNPK Infographic by Boster Bio
All HNRNPK Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01793
100 μl
Cat # M01793
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1280
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1280
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2291
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2291
1 kit, containing two 96-well plates and all necessary reagents
Human, Monkey, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A01793S284-1
100ul
Cat # A01793S284-1
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01793-2
100 μg/vial
Cat # A01793-2
100 μg/vial
HNRNPK Overview
Facts about Heterogeneous nuclear ribonucleoprotein K.
Heterogeneous nuclear ribonucleoprotein K (HNRNPK)
One of the major pre-mRNA-binding proteins. Likely to play a role in the nuclear metabolism of hnRNAs, especially for pre-mRNAs that contain cytidine-rich sequences.
Can also bind poly(C) single- stranded DNA. Plays an essential role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression.
Gene Information
| Human | |
|---|---|
| Gene Name: | HNRNPK |
| Uniprot: | P61978 |
| Entrez: | 3190 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
dC-stretch binding protein; FLJ41122; heterogeneous nuclear ribonucleoprotein K; hnRNP K; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNPHNRPKCSBP
Molecular Weight
Mass (kDA):
50.976 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q21.32 |
| Sequence: | 9; NC_000009.12 (83968083..83980782, complement) |
Subcellular Localizations
Cytoplasm. Nucleus, nucleoplasm. Cell projection, podosome. Recruited to p53/TP53-responsive promoters, in the presence of functional p53/TP53 (PubMed:16360036). In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear (PubMed:18775702).
Diseases
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Blast Phase
- Myeloid Leukemia, Chronic
- Carcinoma
- Myeloid Leukemia
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Fragile X Syndrome
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
Interacting Proteins
- ABI2
- ADRB2
- AQP5
- AURKA
- C6orf226
- CIRBP
- DALRD3
- DOCK2
- GRB2
- HNRNPLL
Pathways
- Translation
- Localization
- Transport
- Cell Cycle
- Cell Proliferation
- Dna Repair
- Nuclear Export
- Mrna Processing
- Rna Processing
- Cell Adhesion
- Cell Migration
- Brain Development
- Proteolysis
PTMs
- Phosphorylation
- Sumoylation
Research Areas
- Cancer
- Core ESC-Like Genes
- DNA Repair
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPK
bosterbio.com/bosterbio-gene-info-cards/HNRNPK
References
PMID: 1729596 by Matunis M.J., et al. Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.
PMID: 8107114 by Dejgaard K., et al. Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing.
1 Publications of Boster HNRNPK Antibodies & ELISA Kits
- PubMed ID: 32855668, Mou Q,Jiang Y,Zhu L,Zhu Z,Ren T.EGCG induces β-defensin 3 against influenza A v...
*More publications can be found for each product on its corresponding product page