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Homer protein homolog 1 Antibodies
AND HOMER1 ELISA kits, Homer protein homolog 1 Proteins
Many biological assays use antibodies to detect Homer protein homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homer protein homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homer protein homolog 1 antibodies...
Designing a Western blot for Homer protein homolog 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HOMER1 Western Blot GuideHOMER1 Infographic by Boster Bio
All HOMER1 Products
Product
Figures
Specificity
Applications
Price
Anti-Homer1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M03877-1
100 μl/vial
Cat # M03877-1
100 μl/vial
Human, Mouse, Rat
IHC, WB
$523
Cat # M03877
100 µl
Cat # M03877
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03877-1
100 μg/vial
Cat # A03877-1
100 μg/vial
HOMER1 Overview
Facts about Homer protein homolog 1.
Homer protein homolog 1 (HOMER1)
Binds and cross-links cytoplasmic areas of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.
May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5.
Gene Information
| Human | |
|---|---|
| Gene Name: | HOMER1 |
| Uniprot: | Q86YM7 |
| Entrez: | 9456 |
Family
| Belongs to: |
|---|
| Homer family |
Alternative Names
homer homolog 1 (Drosophila); HOMER; HOMER1; homer-1; HOMER1A; HOMER1B; HOMER-1B; HOMER1C; SYN47; SYN47neuronal immediate early gene, 1; Ves-1
Molecular Weight
Mass (kDA):
40.277 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q14.1 |
| Sequence: | 5; NC_000005.10 (79372636..79514134, complement) |
Subcellular Localizations
Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cell projection, dendritic spine. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the endoplasmic reticulum.
Diseases
- Pain
- Depressive Disorder
- Stress, Psychological
- Neuralgia
- Hyperalgesia
- Parkinson Disease
- Nervousness
- Peripheral Nerve Injuries
- Psychotic Disorders
- Mood Disorders
- Secondary Parkinson Disease
- Nerve Damage
Interacting Proteins
- ABI3
- C19orf57
- HOMER3
- SARG
- TRAF5
Pathways
- Synaptic Transmission
- Localization
- Neurogenesis
- Sensitization
- Transport
- Aging
- Cognition
- Pathogenesis
- Secretion
- Protein Phosphorylation
- Synapse Maturation
- Electron Transport
- Regulation Of Signal Transduction
PTMs
- Phosphorylation
- Deacetylation
Research Areas
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HOMER1
bosterbio.com/bosterbio-gene-info-cards/HOMER1
References
PMID: 9808458 by Xiao B., et al. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.
PMID: 10464340 by Roche K.W., et al. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors.