JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

HPF1 Antibodies

AND HPF1 ELISA kits, HPF1 Proteins

Many biological assays use antibodies to detect HPF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPF1 antibodies...

We validate the specificity of these antibodies to HPF1 by testing them on tissues known to express HPF1 positively and negatively. Browse below to find the HPF1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: TTC12

HPF1 Infographic by Boster Bio

HPF1 protein infographic

All HPF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

C4orf27 (HPF1) (NM_017867) Human Over-expression Lysate

C4orf27 (HPF1) Human Over-expression Lysates NM_017867

C4orf27 (HPF1) Human Over-expression Lysates NM_017867

Human

$628
Cat # LS054969
20 µg, 100 µg

HPF1 Overview

Facts about Histone PARylation factor 1.

HPF1 3D structure

HPF1 3D structure. Source: alphafold

Histone PARylation factor 1 (HPF1)

Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP1 and is able to alter amino acid specificity toward serine (PubMed:28190768). Promotes histone serine ADP- ribosylation in response to DNA damage, limiting DNA damage- induced PARP1 hyper-automodification, and ensuring genome stability (PubMed:27067600, PubMed:28190768).

.

Gene Information

Human
Gene Name:	HPF1
Uniprot:	Q9NWY4
Entrez:	54969

Gene Information

Family

Belongs to:

HPF1 family

Family

Alternative Names

Histone PARylation factor 1

Molecular Weight

Mass (kDA):
39.436 kDA

Molecular Weight

Genomic Context


Human

Location:	4q33
Sequence:	4; NC_000004.12 (169729470..169757944, complement)

PTMs

Acetylation

ADP-ribosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPF1

References

PMID: 27067600 by Gibbs-Seymour I., et al. HPF1/C4orf27 is a PARP-1-interacting protein that regulates PARP-1 ADP-ribosylation activity.

PMID: 28190768 by Bonfiglio J.J., et al. Serine ADP-ribosylation depends on HPF1.