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- Table of Contents
HPRT1 Antibodies
AND HPRT1 ELISA kits, HPRT1 Proteins
Many biological assays use antibodies to detect HPRT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPRT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPRT1 antibodies...
Designing a Western blot for HPRT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HPRT1 Western Blot GuideHPRT1 Infographic by Boster Bio
All HPRT1 Products
Product
Figures
Specificity
Applications
Price
Anti-HPRT1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A00668-1
100 µg/vial
Cat # A00668-1
100 µg/vial
Anti-HPRT HPRT1 Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M00668
100 μl
Cat # M00668
100 μl
HPRT1 Overview
Facts about Hypoxanthine-guanine phosphoribosyltransferase.
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1)
Converts guanine into guanosine monophosphate, and hypoxanthine into inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.
Plays a central role in the generation of purine nucleotides through the purine salvage pathway. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HPRT1 |
| Uniprot: | P00492 |
| Entrez: | 3251 |
Family
| Belongs to: |
|---|
| purine/pyrimidine phosphoribosyltransferase family |
Alternative Names
EC 2.4.2.8; HGPRT; HGPRT1; HGPRTHPRTHGPRTase; HPRT; HPRT1; hypoxanthine phosphoribosyltransferase 1; hypoxanthine-guanine phosphoribosyltransferase
Molecular Weight
Mass (kDA):
24.579 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq26.2-q26.3 |
| Sequence: | X; NC_000023.11 (134460165..134500668) |
Subcellular Localizations
Cytoplasm.
Diseases
- Lesch-nyhan Syndrome
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Hyperuricemia
- Gout
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Lung
- Obesity
- Kidney Neoplasm
- Mammary Neoplasms
- Lung Neoplasms
Interacting Proteins
- ISCU
- PRTFDC1
- SDCBP
- WDYHV1
Pathways
- Reverse Transcription
- Regeneration
- Aging
- Dosage Compensation
- Embryo Development
- Cell Proliferation
- Methylation
- Pathogenesis
- Gene Silencing
- Osteoblast Differentiation
- Fertilization
- Immune Response
- Inflammatory Response
PTMs
- Methylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPRT1
bosterbio.com/bosterbio-gene-info-cards/HPRT1
References
PMID: 6300847 by Jolly D.J., et al. Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.
PMID: 2341149 by Edwards A., et al. Automated DNA sequencing of the human HPRT locus.