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HPS4 Antibodies

AND HPS4 ELISA kits, HPS4 Proteins

Many biological assays use antibodies to detect HPS4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPS4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPS4 antibodies...

We validate the specificity of these antibodies to HPS4 by testing them on tissues known to express HPS4 positively and negatively. Browse below to find the HPS4 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HPS4 Infographic by Boster Bio

HPS4 protein infographic

All HPS4 Products

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Product

Figures

Specificity

Applications

Price

Anti-HPS4 Antibody

Western blot analysis of extracts of U-87MG cells, using HPS4 antibody at 1:1000 dilution

Western blot analysis of extracts of U-87MG cells, using HPS4 antibody at 1:1000 dilution

Immunofluorescence analysis of C6 cells using HPS4 antibody at dilution of 1:100

Immunofluorescence analysis of L929 cells using HPS4 antibody at dilution of 1:100

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06241
100ul

HPS4 (NM_022081) Human Recombinant Protein

Coomassie blue staining of purified HPS4 protein

Coomassie blue staining of purified HPS4 protein

$1249
Cat # PROTQ9NQG7
20 µg

HPS4 (NM_022081) Human Over-expression Lysate

HPS4 Human Over-expression Lysates NM_022081

HPS4 Human Over-expression Lysates NM_022081

Human

$628
Cat # LS089781
20 µg, 100 µg

Anti-HPS4 Antibody

boster box

Human

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A06241-1
100 μl/vial

HPS4 Overview

Facts about Hermansky-Pudlak syndrome 4 protein.

HPS4 3D structure

HPS4 3D structure. Source: alphafold

Hermansky-Pudlak syndrome 4 protein (HPS4)

Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 (PubMed:23084991).

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Gene Information

Human
Gene Name:	HPS4
Uniprot:	Q9NQG7
Entrez:	89781

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

Hermansky-Pudlak syndrome 4 protein

Molecular Weight

Mass (kDA):
76.919 kDA

Molecular Weight

Genomic Context


Human

Location:	22q12.1
Sequence:	22; NC_000022.11 (26443109..26483863, complement)

Diseases

Hermansky-Pudlak syndrome 4 (HPS4)

Disease

Interacting Proteins

HPS1

Interacting Proteins

PTMs

Phosphoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPS4

References

PMID: 11836498 by Suzuki T., et al. Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene.

PMID: 12529303 by Collins J.E., et al. Reevaluating human gene annotation: a second-generation analysis of chromosome 22.