HRC Antibodies

AND HRC ELISA kits, HRC Proteins

Many biological assays use antibodies to detect HRC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HRC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HRC antibodies...

We validate the specificity of these antibodies to HRC by testing them on tissues known to express HRC positively and negatively. Browse below to find the HRC antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HRC Infographic by Boster Bio

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HRC Overview

Facts about Sarcoplasmic reticulum histidine-rich calcium-binding protein.

HRC 3D structure. Source: alphafold

Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC)

May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. .

Gene Information

Human
Gene Name:	HRC
Uniprot:	P23327
Entrez:	3270

Family

Belongs to:

HRC family

Alternative Names

HCP; histidine rich calcium binding protein; MGC133236; sarcoplasmic reticulum histidine-rich calcium-binding protein

Molecular Weight

Mass (kDA):
80.244 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49151198..49155464, complement)

Subcellular Localizations

Sarcoplasmic reticulum lumen.

Diseases

Neoplasms
Heart Failure
Systemic Infection
Sepsis Neonatal
Anemia
Cardiac Arrhythmia
Hiv Infections
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Hypertrophy
Diabetes Mellitus
Glioma

Carcinoma
Leukemia
Diabetes Mellitus, Non-insulin-dependent
Cell Transformation, Neoplastic
Infant, Very Low Birth Weight
Kidney Failure, Chronic
Astrocytoma

Interacting Proteins

Ryr2

Pathways

Pathogenesis
Transport
Localization
Regulation Of Gene Expression
Cell Activation
Aging
Sulfate Reduction
Muscle Contraction
Translation
Rna Transport
Cell Cycle
Entry Into Host
Membrane Fusion

Cell Death
Brain Development
Immune Response
B Cell Activation
Cardiac Conduction
Reflex
Cell Division

PTMs

Phosphorylation
Cleavage

Biotinylation
Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HRC

References

PMID: 2037293 by Hofmann S.L., et al. cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7.