HS3ST6 Antibodies

AND HS3ST6 ELISA kits, HS3ST6 Proteins

Many biological assays use antibodies to detect HS3ST6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HS3ST6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HS3ST6 antibodies...

We validate the specificity of these antibodies to HS3ST6 by testing them on tissues known to express HS3ST6 positively and negatively. Browse below to find the HS3ST6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HS3ST6 Infographic by Boster Bio

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HS3ST6 (NM_001009606) Human Over-expression Lysate

Human

$628
Cat # LS064711
20 µg, 100 µg

HS3ST6 Overview

Facts about Heparan sulfate glucosamine 3-O-sulfotransferase 6.

HS3ST6 3D structure. Source: alphafold

Heparan sulfate glucosamine 3-O-sulfotransferase 6 (HS3ST6)

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry.

Unlike 3- OST-1, doesn't convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. .

Gene Information

Human
Gene Name:	HS3ST6
Uniprot:	Q96QI5
Entrez:	64711

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

h3-OST-6; heparan sulfate (glucosamine) 3-O-sulfotransferase 6; heparan sulfate 3-O-sulfotransferase 6; heparan sulfate glucosamine 3-O-sulfotransferase 6; HS3ST5

Molecular Weight

Mass (kDA):
37.186 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1911475..1921428, complement)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Conjunctival Diseases
Dry Eye Syndromes

Pathways

Notch Signaling Pathway
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HS3ST6

References

PMID: 15303968 by Xu D., et al. Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1.