HADHB Antibodies

AND HADHB ELISA kits, HADHB Proteins

Many biological assays use antibodies to detect HADHB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HADHB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HADHB antibodies...

We validate the specificity of these antibodies to HADHB by testing them on tissues known to express HADHB positively and negatively. Browse below to find the HADHB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for HADHB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the HADHB IHC Guide

HADHB Infographic by Boster Bio

All HADHB Products

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Product

Figures

Specificity

Applications

Price

Anti-HADHB Antibody Picoband®

Western blot analysis of HADHB using anti-HADHB antibody (A04776-2)

IHC analysis of HADHB using anti-HADHB antibody (A04776-2)

+10

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04776-2
100 µg/vial

HADHB (NM_000183) Human Over-expression Lysate

Human

$628
Cat # LS003032
20 µg, 100 µg

Human HADHB Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP55084
Starting from 20ug

HADHB Overview

Facts about Trifunctional enzyme subunit beta, mitochondrial.

HADHB 3D structure. Source: alphafold

Trifunctional enzyme subunit beta, mitochondrial (HADHB)

Gene Information

Human
Gene Name:	HADHB
Uniprot:	P55084
Entrez:	3032

Family

Belongs to:

thiolase-like superfamily

Alternative Names

2-enoyl-Coenzyme A (CoA) hydratase, beta subunit; 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein; acetyl-CoA acyltransferase; beta subunit; beta-ketothiolase; EC 2.3.1; EC 2.3.1.16; ECHB; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase(trifunctional protein), beta subunit; hydroxyacyl-Coenzyme A (CoA) dehydrogenase, beta subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme Athiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; MGC87480; mitochondrial trifunctional enzyme, beta subunit; mitochondrial trifun

Molecular Weight

Mass (kDA):
51.294 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (26244748..26290465)

Subcellular Localizations

Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Endoplasmic reticulum. Protein stability and association with membranes require HADHA.

Diseases

Mitochondrial Trifunctional Protein Deficiency
Protein Deficiency
Cardiomyopathies
Abetalipoproteinemia
Atherosclerosis
Metabolic Diseases
Dyslipidemias
Malignant Neoplasms
Acidosis
Obesity
Malignant Neoplasm Of Breast
Mitochondrial Diseases
Myopathy

Hypoglycemia
Fatty Liver
Heart Failure
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Acidosis, Lactic
Cardiovascular Diseases

Interacting Proteins

GABARAPL1

Pathways

Fatty Acid Oxidation
Localization
Translation
Fatty Acid Beta-oxidation
Transport
Energy Homeostasis
Cholesterol Efflux
Cholesterol Homeostasis
Cell Proliferation
Dna Methylation
Regulation Of Gene Expression
Oxidative Phosphorylation
Methylation

Fatty Acid Homeostasis
Mrna Stabilization
Reverse Cholesterol Transport
Lipid Homeostasis
Cell Differentiation
Cholesterol Transport
Rna Interference

PTMs

Oxidation
Reduction

Cleavage
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HADHB

References

PMID: 8135828 by Kamijo T., et al. Structural analysis of cDNAs for subunits of human mitochondrial fatty acid beta-oxidation trifunctional protein.

PMID: 9259266 by Orii K.E., et al. Genomic and mutational analysis of the mitochondrial trifunctional protein beta-subunit (HADHB) gene in patients with trifunctional protein deficiency.