Histone H2B type 2-B Antibodies

AND Hist2h2bb ELISA kits, Histone H2B type 2-B Proteins

Many biological assays use antibodies to detect Histone H2B type 2-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone H2B type 2-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone H2B type 2-B antibodies...

We validate the specificity of these antibodies to Histone H2B type 2-B by testing them on tissues known to express Hist2h2bb positively and negatively. Browse below to find the Hist2h2bb antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hist2h2bb Infographic by Boster Bio

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Hist2h2bb Overview

Facts about Histone H2B type 2-B.

Hist2h2bb 3D structure. Source: alphafold

Histone H2B type 2-B (Hist2h2bb)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Mouse
Gene Name:	Hist2h2bb
Uniprot:	Q64525
Entrez:

Family

Belongs to:

histone H2B family

Alternative Names

Histone H2B type 2-B

Molecular Weight

Mass (kDA):
13.92 kDA

Genomic Context


Mouse

Location:
Sequence:	;

PTMs

Acetylation
Hydroxylation
Isopeptide bond

Methylation
Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hist2h2bb

References

PMID: 8858345 by Wang Z.-F., et al. Characterization of the 55-kb mouse histone gene cluster on chromosome 3.

PMID: 15197225 by Fernandez-Capetillo O., et al. Phosphorylation of histone H2B at DNA double-strand breaks.