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- Table of Contents
Designing an IHC experiment for 3-keto-steroid reductase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HSD17B7 IHC GuideFacts about 3-keto-steroid reductase.
Responsible for the reduction of the keto group on the C-3 of sterols.
.| Mouse | |
|---|---|
| Gene Name: | Hsd17b7 |
| Uniprot: | O88736 |
| Entrez: | 15490 |

| Belongs to: |
|---|
| short-chain dehydrogenases/reductases (SDR) family |

17 beta-hydroxysteroid dehydrogenase type VII; 17-beta-hydroxysteroid dehydrogenase 7; 3-keto-steroid reductase; EC 1.1.1.270; EC 1.1.1.62; Estradiol 17-beta-dehydrogenase 7; hydroxysteroid (17-beta) dehydrogenase 7,17beta hydroxysteroid dehydrogenase; MGC12523; MGC75018,17-beta-HSD 7; PRAP; SDR37C1; short chain dehydrogenase/reductase family 37C, member 1
Mass (kDA):
37.317 kDA

| Mouse | |
|---|---|
| Location: | 1|1 H3 |
| Sequence: | 1; |
Most abundant in ovaries of pregnant animals. Present also in nonpregnant animals in ovaries, mammary gland, liver, kidney and testis.



PMID: 9658408 by Nokelainen P., et al. Expression cloning of a novel estrogenic mouse 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat.