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- Table of Contents
Islet amyloid polypeptide Antibodies
AND IAPP ELISA kits, Islet amyloid polypeptide Proteins
Many biological assays use antibodies to detect Islet amyloid polypeptide, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Islet amyloid polypeptide in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Islet amyloid polypeptide antibodies...
Designing an IHC experiment for Islet amyloid polypeptide? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the IAPP IHC GuideIAPP Infographic by Boster Bio
All IAPP Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$480
Cat # EKC1028
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1028
1 kit, containing one 96-well plate and all necessary reagents
IAPP Overview
Facts about Islet amyloid polypeptide.
Islet amyloid polypeptide (IAPP)
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IAPP |
| Uniprot: | P10997 |
| Entrez: | 3375 |
Family
| Belongs to: |
|---|
| calcitonin family |
Alternative Names
AMYLIN; DAPamylin; Diabetes-associated peptide; IAP; Insulinoma amyloid peptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); islet amyloid polypeptide
Molecular Weight
Mass (kDA):
9.806 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p12.1 |
| Sequence: | 12; NC_000012.12 (21354960..21379980) |
Subcellular Localizations
Secreted.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Plaque, Amyloid
- Insulinoma
- Insulin Resistance
- Amyloidosis
- Hyperglycemia
- Alzheimer's Disease
- Pancreatic Neoplasm
- Amyloid Deposition
- Obesity
- Diabetes Mellitus, Insulin-dependent
Interacting Proteins
- BACE1
- BACE2
Pathways
- Secretion
- Insulin Secretion
- Pathogenesis
- Cell Death
- Amyloid Fibril Formation
- Localization
- Glucose Homeostasis
- Hormone Secretion
- Gastric Emptying
- Aging
- Secretory Pathway
- Transport
- Glucagon Secretion
PTMs
- Amidation
- Cleavage
- Methylation
- Oxidation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IAPP
bosterbio.com/bosterbio-gene-info-cards/IAPP
References
PMID: 2651160 by Mosselman S., et al. The complete islet amyloid polypeptide precursor is encoded by two exons.
PMID: 2608057 by Nishi M., et al. Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history.
3 Publications of Boster Islet amyloid polypeptide Antibodies & ELISA Kits
- PubMed ID: 10.3389/fnagi.2019.00225, High-Fat Diet Increases Amylin Accumulation in the Hippocampus and Accelerates B...
- PubMed ID: 31507407, Xi XX,Sun J,Chen HC,Chen AD,Gao LP,Yin J,Jing YH.High-Fat Diet Increases Amylin ...
- PubMed ID: 31507407, High-Fat Diet Increases Amylin Accumulation in the Hippocampus and Accelerates B...
*More publications can be found for each product on its corresponding product page