IARS2 Antibodies

AND IARS2 ELISA kits, IARS2 Proteins

Many biological assays use antibodies to detect IARS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IARS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IARS2 antibodies...

We validate the specificity of these antibodies to IARS2 by testing them on tissues known to express IARS2 positively and negatively. Browse below to find the IARS2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for IARS2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the IARS2 IHC Guide

IARS2 Infographic by Boster Bio

All IARS2 Products

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Anti-IARS2 Antibody Picoband®

Western blot analysis of IARS2 using anti-IARS2 antibody (A09580-2)

IHC analysis of IARS2 using anti-IARS2 antibody (A09580-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A09580-2
100 µg/vial

IARS2 Overview

Facts about Isoleucine--tRNA ligase, mitochondrial.

IARS2 3D structure. Source: alphafold

Isoleucine--tRNA ligase, mitochondrial (IARS2)

Gene Information

Human
Gene Name:	IARS2
Uniprot:	Q9NSE4
Entrez:	55699

Family

Belongs to:

class-I aminoacyl-tRNA synthetase family

Alternative Names

EC 6.1.1; EC 6.1.1.5; FLJ10326; ILERS; isoleucine tRNA ligase 2, mitochondrial; Isoleucine--tRNA ligase; isoleucine-tRNA synthetase 2, mitochondrial; isoleucyl-tRNA synthetase 2, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase

Molecular Weight

Mass (kDA):
113.792 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (220094132..220148041)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Hypertrophic Cardiomyopathy
Cell Transformation, Neoplastic
Cardiomyopathies
Malignant Neoplasms
Ischemia
Hypertrophy
Transient Ischemic Attack

Brain Injuries

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IARS2

References

PMID: 25130867 by Schwartzentruber J., et al. Mutation in the nuclear-encoded mitochondrial isoleucyl-tRNA synthetase IARS2 in patients with cataracts, growth hormone deficiency with short stature, partial sensorineural deafness, and peripheral neuropathy or with Leigh syndrome.