ICE2 Antibodies

AND ICE2 ELISA kits, ICE2 Proteins

Many biological assays use antibodies to detect ICE2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ICE2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ICE2 antibodies...

We validate the specificity of these antibodies to ICE2 by testing them on tissues known to express ICE2 positively and negatively. Browse below to find the ICE2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ICE2 Infographic by Boster Bio

All ICE2 Products

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Caspase 10 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HeLa cells

Human

ELISA

$480
Cat # EKC1084
1 kit, containing one 96-well plate and all necessary reagents

ICE2 Overview

Facts about Little elongation complex subunit 2.

ICE2 3D structure. Source: alphafold

Little elongation complex subunit 2 (ICE2)

Component of the little elongation complex (LEC), a complex necessary to control small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. .

Gene Information

Human
Gene Name:	ICE2
Uniprot:	Q659A1
Entrez:	79664

Family

Belongs to:

ICE2 family

Alternative Names

Little elongation complex subunit 2

Molecular Weight

Mass (kDA):
110.011 kDA

Genomic Context


Human

Location:	15q22.2
Sequence:	15; NC_000015.10 (60419609..60479142, complement)

Tissue Specificity

Expressed at low levels in lung and testis.

Subcellular Localizations

Nucleus. Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Translocates in the LEC complex to Cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ICE2

References

PMID: 15606750 by Sugiura N., et al. NARG2 encodes a novel nuclear protein with (S/T)PXX motifs that is expressed during development.

PMID: 22195968 by Smith E.R., et al. The little elongation complex regulates small nuclear RNA transcription.