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- Table of Contents
Facts about Interferon alpha-inducible protein 6.
Has an antiviral action towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571). .
| Human | |
|---|---|
| Gene Name: | IFI6 |
| Uniprot: | P09912 |
| Entrez: | 2537 |

| Belongs to: |
|---|
| IFI6/IFI27 family |

Interferon alpha-inducible protein 6
Mass (kDA):
12.927 kDA

| Human | |
|---|---|
| Location: | 1p35.3 |
| Sequence: | 1; NC_000001.11 (27666061..27672229, complement) |
Mitochondrion inner membrane; Multi-pass membrane protein.


PMID: 3017706 by Kelly J.M., et al. Characterization of a human gene inducible by alpha- and beta- interferons and its expression in mouse cells.
PMID: 7596809 by Turri M.G., et al. Characterisation of a novel minisatellite that provides multiple splice donor sites in an interferon-induced transcript.