IFT140 Antibodies

AND IFT140 ELISA kits, IFT140 Proteins

Many biological assays use antibodies to detect IFT140, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IFT140 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IFT140 antibodies...

We validate the specificity of these antibodies to IFT140 by testing them on tissues known to express IFT140 positively and negatively. Browse below to find the IFT140 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IFT140 Infographic by Boster Bio

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IFT140 Overview

Facts about Intraflagellar transport protein 140 homolog.

IFT140 3D structure. Source: alphafold

Intraflagellar transport protein 140 homolog (IFT140)

Part of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport (PubMed:20889716, PubMed:22503633). Plays a pivotal role in proper development and function of ciliated cells through its function in ciliogenesis and/or cilium maintenance (PubMed:22503633).

Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity).

Gene Information

Human
Gene Name:	IFT140
Uniprot:	Q96RY7
Entrez:	9742

Family

Belongs to:

No superfamily

Alternative Names

Intraflagellar transport protein 140 homolog

Molecular Weight

Mass (kDA):
165.193 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (1510427..1612072, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.

Diseases

Short-rib thoracic dysplasia 9 with or without polydactyly (SRTD9)

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IFT140

References

PMID: 20889716 by Mukhopadhyay S., et al. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.

PMID: 22503633 by Perrault I., et al. Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations.