IFT46 Antibodies

AND IFT46 ELISA kits, IFT46 Proteins

Many biological assays use antibodies to detect IFT46, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IFT46 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IFT46 antibodies...

We validate the specificity of these antibodies to IFT46 by testing them on tissues known to express IFT46 positively and negatively. Browse below to find the IFT46 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IFT46 Infographic by Boster Bio

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IFT46 (NM_020153) Human Over-expression Lysate

Human

$628
Cat # LS056912
20 µg, 100 µg

IFT46 Overview

Facts about Intraflagellar transport protein 46 homolog.

IFT46 3D structure. Source: alphafold

Intraflagellar transport protein 46 homolog (IFT46)

Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles necessary for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity).

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Gene Information

Human
Gene Name:	IFT46
Uniprot:	Q9NQC8
Entrez:	56912

Family

Belongs to:

IFT46 family

Alternative Names

C11orf2UPF0360; C11orf60; chromosome 11 open reading frame 60; FLJ21827; intraflagellar transport 46 homolog (Chlamydomonas); intraflagellar transport protein 46 homolog; intraflagellar transport protein IFT46

Molecular Weight

Mass (kDA):
34.286 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (118544528..118576456, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Expression is concentrated at the cilium basal body but is also detected along the length of the cilium.

Diseases

Hypertrophy
Suppressor Mutation
Superior Oblique Overaction

Pathways

Transport
Intraflagellar Transport
Localization
Cell Division
Endochondral Ossification
Cell Cycle
G1 Phase

M Phase
Ossification

PTMs

Phosphorylation

Cleavage

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IFT46

References

PMID: 10873569 by O'Brien K.P., et al. Characterization of five novel human genes in the 11q13-q22 region.

PMID: 24339792 by Cevik S., et al. Active transport and diffusion barriers restrict Joubert syndrome- associated ARL13B/ARL-13 to an inv-like ciliary membrane subdomain.