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- Table of Contents
Facts about Immunoglobulin heavy variable 3-43D.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).
Human | |
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Gene Name: | IGHV3-43D |
Uniprot: | P0DP04 |
Entrez: | 103106901 |
Belongs to: |
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No superfamily |
Immunoglobulin heavy variable 3-43D
Mass (kDA):
13.017 kDA
Human | |
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Location: | 14q32.33 |
Sequence: | 14; |
Secreted. Cell membrane.
PMID: 23541343 by Watson C.T., et al. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.