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- Table of Contents
Facts about Immunoglobulin lambda constant 6.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).
| Human | |
|---|---|
| Gene Name: | IGLC6 |
| Uniprot: | P0CF74 |
| Entrez: | 3542 |

| Belongs to: |
|---|
| No superfamily |

Immunoglobulin lambda constant 6
Mass (kDA):
11.277 kDA

| Human | |
|---|---|
| Location: | 22q11.22 |
| Sequence: | 22; NC_000022.11 (22919535..22919858) |
Secreted. Cell membrane.


PMID: 6273747 by Hieter P.A., et al. Clustered arrangement of immunoglobulin lambda constant region genes in man.
PMID: 3122211 by Dariavach P., et al. Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes.