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- Table of Contents
Facts about Interleukin-1 receptor type 2.
Non-signaling receptor for IL1A, IL1B and IL1RN.
Reduces IL1B activities.Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also governs cellular response through non-signaling association with IL1RAP after binding to IL1B.
Human | |
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Gene Name: | IL1R2 |
Uniprot: | P27930 |
Entrez: | 7850 |
Belongs to: |
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interleukin-1 receptor family |
beta; CD121b antigen; CD121b; IL-1 R beta; IL-1 RII; IL1R2; IL1RBCD121 antigen-like family member B; IL-1R-beta; IL1RII; IL-1RII; IL-1RT2; IL-1RT-2; interleukin 1 receptor, type II; Interleukin-1 receptor beta; MGC47725
Mass (kDA):
45.421 kDA
Human | |
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Location: | 2q11.2 |
Sequence: | 2; NC_000002.12 (101991805..102028544) |
[Isoform Short]: Secreted.; [Isoform Long]: Cell membrane; Single-pass type I membrane protein.
Boster Bio is not a new name. This article will discuss the Boster Bio Anti-IL1R2 marker and its best use. Here are some samples:
Boster Bio has a range of biological assays using the anti-IL1R2 markers. The antibody reacts with both human and mouse samples. The company was founded 1993 and is a leading supplier of picogram sensitive ELISA tests and research antibodies. Boster Bio's anti-bodies are sensitive and have been evaluated against more than 250 different types of cell lines and tissue samples. The antibody can also be used in immunofluorescence, flow cytometry and ELISA tests.
The antibody is approved as an immunohistochemistry tool and detects IL-1a-expressing cells from human and rat. The antigen is formulated with 0.05 mg Thimerosal (aa249-269) and 5 grams of BSA (as BSA). The antigen reacts to human IL-1 beta (aa249-269).
PMID: 1833184 by McMahan C.J., et al. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.
PMID: 8702856 by Liu C., et al. Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA.