IL1R2 Antibodies

Interleukin-1 receptor type 2 (IL1R2)

Non-signaling receptor for IL1A, IL1B and IL1RN.

Reduces IL1B activities.

Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also governs cellular response through non-signaling association with IL1RAP after binding to IL1B.

Gene Information

Human
Gene Name:	IL1R2
Uniprot:	P27930
Entrez:	7850

Family

Belongs to:
interleukin-1 receptor family

Alternative Names

beta; CD121b antigen; CD121b; IL-1 R beta; IL-1 RII; IL1R2; IL1RBCD121 antigen-like family member B; IL-1R-beta; IL1RII; IL-1RII; IL-1RT2; IL-1RT-2; interleukin 1 receptor, type II; Interleukin-1 receptor beta; MGC47725

Molecular Weight

Mass (kDA):
45.421 kDA

Genomic Context

Human
Location:	2q11.2
Sequence:	2; NC_000002.12 (101991805..102028544)

Subcellular Localizations

[Isoform Short]: Secreted.; [Isoform Long]: Cell membrane; Single-pass type I membrane protein.

Diseases

• Inflammation
• Endometrial Polyp
• Malignant Neoplasms
• Endometriosis, Site Unspecified
• Inflammatory Response
• Ankylosing Spondylitis
• Asthma
• Spondylitis
• Tumor Angiogenesis
• Infertility
• Ulcer
• Neoplasms
• Osteoarthritis, Spine

• Tissue Adhesions
• Inflammatory Bowel Diseases
• Autoimmune Diseases
• Diabetes Mellitus
• Crohn Disease
• Colitis
• Ulcerative Colitis

Interacting Proteins

• IL1A

Pathways

• Pathogenesis
• Inflammatory Response
• Immune Response
• Secretion
• Angiogenesis
• Cell Proliferation
• Cell Growth
• Cell Adhesion
• Cell Activation
• Cell Cycle
• Decidualization
• Coagulation
• Rna Interference

• Cell Migration
• Dna Hypomethylation
• Aging
• Pigmentation
• Keratinocyte Differentiation
• Embryo Development
• Embryo Implantation

PTMs

• Phosphorylation

• Acetylation

• Methylation

Research Areas

• Cancer
• Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL1R2

Boster Bio - Best Uses Of The IL1R2 Marker

Boster Bio is not a new name. This article will discuss the Boster Bio Anti-IL1R2 marker and its best use. Here are some samples:

Boster Bio Anti-IL1R2 Marker

Boster Bio has a range of biological assays using the anti-IL1R2 markers. The antibody reacts with both human and mouse samples. The company was founded 1993 and is a leading supplier of picogram sensitive ELISA tests and research antibodies. Boster Bio's anti-bodies are sensitive and have been evaluated against more than 250 different types of cell lines and tissue samples. The antibody can also be used in immunofluorescence, flow cytometry and ELISA tests.

The antibody is approved as an immunohistochemistry tool and detects IL-1a-expressing cells from human and rat. The antigen is formulated with 0.05 mg Thimerosal (aa249-269) and 5 grams of BSA (as BSA). The antigen reacts to human IL-1 beta (aa249-269).