IMMT Antibodies

AND IMMT ELISA kits, IMMT Proteins

Many biological assays use antibodies to detect IMMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IMMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IMMT antibodies...

We validate the specificity of these antibodies to IMMT by testing them on tissues known to express IMMT positively and negatively. Browse below to find the IMMT antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for IMMT? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the IMMT Western Blot Guide

Designing an IHC experiment for IMMT? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the IMMT IHC Guide

IMMT Infographic by Boster Bio

All IMMT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Mitofilin/IMMT Antibody Picoband®

Western blot analysis of Mitofilin/IMMT using anti-Mitofilin/IMMT antibody (A04102-2)

IHC analysis of Mitofilin/IMMT using anti-Mitofilin/IMMT antibody (A04102-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04102-2
100 µg/vial

Mitofilin (IMMT) (NM_006839) Human Over-expression Lysate

Human

$628
Cat # LS010989
20 µg, 100 µg

IMMT Overview

Facts about MICOS complex subunit MIC60.

IMMT 3D structure. Source: alphafold

MICOS complex subunit MIC60 (IMMT)

Part of the MICOS complicated, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, internal membrane architecture, and formation of contact sites to the outer membrane. Plays an essential role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).

Gene Information

Human
Gene Name:	IMMT
Uniprot:	Q16891
Entrez:	10989

Family

Belongs to:

MICOS complex subunit Mic60 family

Alternative Names

DKFZp779P1653; inner membrane protein, mitochondrial; MGC111146; Mic 60; Mic60; MICOS Complex Subunit MIC60; mitochondrial (mitofilin); mitofilin; motor protein; p87/89; proliferation-inducing gene 4

Molecular Weight

Mass (kDA):
83.678 kDA

Genomic Context


Human

Location:	2p11.2\|2
Sequence:	2; NC_000002.12 (86143932..86195770, complement)

Subcellular Localizations

Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion.

Diseases

Neoplasms
Melanoma
Down Syndrome
Neoplasm Metastasis
Reperfusion Injury
Malnutrition
Overlying Behavior
Heart Injuries
Neurodegenerative Disorders
Tumor Progression
Ataxia

Aniridia Type 2
Glioma
Bone Neoplasms
Parkinson Disease
Osteosarcoma
Age Related Macular Degeneration

Interacting Proteins

CHCHD10
DISC1
KDM1A
NDEL1
PDE4DIP

PDHA1

Pathways

Proteolysis
Oxidative Phosphorylation
Protein Import
Pathogenesis
Membrane Organization
Immune Response
Humoral Immune Response
Localization
Translation

Mitochondrial Fission
Mitochondrial Translation
Cell Growth
Exocytosis

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Cellular Markers
Lipid and Metabolism
Mitochondrial Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IMMT

References

PMID: 8039717 by Icho T., et al. A novel human gene that is preferentially transcribed in heart muscle.

PMID: 9168817 by Gieffers C., et al. Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms.