IMPG2 Antibodies

AND IMPG2 ELISA kits, IMPG2 Proteins

Many biological assays use antibodies to detect IMPG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IMPG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IMPG2 antibodies...

We validate the specificity of these antibodies to IMPG2 by testing them on tissues known to express IMPG2 positively and negatively. Browse below to find the IMPG2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for IMPG2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the IMPG2 IHC Guide

IMPG2 Infographic by Boster Bio

All IMPG2 Products

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Anti-IMPG2 Antibody Picoband®

Western blot analysis of IMPG2 using anti-IMPG2 antibody (A10288-1)

IHC analysis of IMPG2 using anti-IMPG2 antibody (A10288-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A10288-1
100 µg/vial

IMPG2 Overview

Facts about Interphotoreceptor matrix proteoglycan 2.

IMPG2 3D structure. Source: alphafold

Interphotoreceptor matrix proteoglycan 2 (IMPG2)

Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin.

Gene Information

Human
Gene Name:	IMPG2
Uniprot:	Q9BZV3
Entrez:	50939

Family

Belongs to:

No superfamily

Alternative Names

interphotoreceptor matrix proteoglycan 2; interphotoreceptor matrix proteoglycan 200; Interphotoreceptor matrix proteoglycan of 200 kDa; IPM 200; IPM200SPACRCAN; RP56; Sialoprotein associated with cones and rods proteoglycan; Spacrcan

Molecular Weight

Mass (kDA):
138.621 kDA

Genomic Context


Human

Location:	3q12.3
Sequence:	3; NC_000003.12 (101222546..101320575, complement)

Tissue Specificity

Expressed in the retina. Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones. IPM occupies the subretinal space between the apices of the retinal pigment epithelium and the neural retina. Detected in the pineal gland.

Subcellular Localizations

Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.

Diseases

Retinal Diseases
Retinal Degeneration
Retinitis Pigmentosa
Abnormal Degeneration
Amaurosis
Cerebellar Neoplasms
Age Related Macular Degeneration
Leber Congenital Amaurosis
Maculopathy
Neoplasms

Headache
Dental Plaque
Medulloblastoma
Optic Atrophy, Hereditary, Leber

Pathways

Glycosylation
Pineal Gland Development
Gland Development
Localization

PTMs

Glycosylation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IMPG2

References

PMID: 10542133 by Kuehn M.H., et al. Molecular characterization and genomic mapping of human IPM 200, a second member of a novel family of proteoglycans.

PMID: 10702256 by Acharya S., et al. SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes.