INTS1 Antibodies

AND INTS1 ELISA kits, INTS1 Proteins

Many biological assays use antibodies to detect INTS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INTS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INTS1 antibodies...

We validate the specificity of these antibodies to INTS1 by testing them on tissues known to express INTS1 positively and negatively. Browse below to find the INTS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: OR1F2P

INTS1 Infographic by Boster Bio

All INTS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

INTS1 (NM_001080453) Human Over-expression Lysate

Human

$960
Cat # LS026173
20 µg, 100 µg

Anti-INTS1 Antibody Picoband®

Western blot analysis of INTS1 using anti-INTS1 antibody (A11979-1)

IHC analysis of INTS1 using anti-INTS1 antibody (A11979-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A11979-1
100 μg/vial

INTS1 Overview

Facts about Integrator complex subunit 1.

INTS1 3D structure. Source: alphafold

Integrator complex subunit 1 (INTS1)

Part of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is linked to the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable).

Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). .

Gene Information

Human
Gene Name:	INTS1
Uniprot:	Q8N201
Entrez:	26173

Family

Belongs to:

Integrator subunit 1 family

Alternative Names

DKFZp586J0619; FLJ46624; integrator complex subunit 1; NET28; UNQ1821/PRO3434

Molecular Weight

Mass (kDA):
244.297 kDA

Genomic Context


Human

Location:	7p22.3
Sequence:	7; NC_000007.14 (1470277..1504389, complement)

Subcellular Localizations

Nucleus membrane; Single-pass membrane protein.

Diseases

Growth Arrest

Pathways

Snrna 3'-end Processing
Cell Death
U2 Snrna 3'-end Processing
Localization

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INTS1

References

PMID: 16239144 by Baillat D., et al. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

PMID: 23904267 by Jodoin J.N., et al. Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.