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- Table of Contents
Integrin alpha-4 Antibodies
AND ITGA4 ELISA kits, Integrin alpha-4 Proteins
Many biological assays use antibodies to detect Integrin alpha-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-4 antibodies...
Designing a Western blot for Integrin alpha-4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGA4 Western Blot GuideITGA4 Infographic by Boster Bio
All ITGA4 Products
Product
Figures
Specificity
Applications
Price
Anti-Integrin alpha 4/ITGA4 Antibody Picoband®
5 Citations
Human, Rat
Flow Cytometry, IHC, IHC-F, WB
$370
Cat # PB9648
100 μg/vial
Cat # PB9648
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00468-2
100 µg/vial
Cat # A00468-2
100 µg/vial
Human
IHC, WB
$449
Cat # M00468-1
100uL
Cat # M00468-1
100uL
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00468-2
100 μg
Cat # M00468-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00468-5
100 μg
Cat # M00468-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00468-4
100 μg
Cat # M00468-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00468-3
100 μg
Cat # M00468-3
100 μg
Human
$960
Cat # LS003676
20 µg, 100 µg
Cat # LS003676
20 µg, 100 µg
Human, Mouse
ELISA, IF, IHC
$380
Cat # A00468S1027
100ul
Cat # A00468S1027
100ul
ITGA4 Overview
Facts about Integrin alpha-4.
Integrin alpha-4 (ITGA4)
They recognize one or more domain names within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1.
Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA4 |
| Uniprot: | P13612 |
| Entrez: | 3676 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
269C wild type; CD49 antigen-like family member D; CD49d antigen; CD49d; CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor; IA4; Integrin alpha 4; integrin alpha-4 subunit; integrin alpha-4; Integrin alpha-IV; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); ITGA4; MGC90518; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha; VLA-4
Molecular Weight
Mass (kDA):
114.9 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q31.3 |
| Sequence: | 2; NC_000002.12 (181456892..181538940) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Autistic Disorder
- Tumor Angiogenesis
- Colorectal Neoplasms
- Colorectal Cancer
- Adenoma
- Malignant Neoplasm Of Breast
- Dysequilibrium Syndrome
- Granuloma
Interacting Proteins
- Ap2m1
- ITGB1
- ITGB7
- PXN
- TGFB1I1
Pathways
- Methylation
- Cell Proliferation
- Angiogenesis
- Pathogenesis
- Cell Adhesion
- Fertilization
- Immune Response
- Dna Methylation
- Localization
- Cell Migration
- Macromolecule Biosynthetic Process
- Biosynthetic Process
- Endothelial Cell Proliferation
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA4
bosterbio.com/bosterbio-gene-info-cards/ITGA4
References
PMID: 2788572 by Takada Y., et al. The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
PMID: 1551405 by Rubio M., et al. A single mRNA encodes the alpha 150 and alpha 80/70 forms of the alpha subunit of VLA4.