ITIH2 Antibodies

AND ITIH2 ELISA kits, ITIH2 Proteins

Many biological assays use antibodies to detect ITIH2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ITIH2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ITIH2 antibodies...

We validate the specificity of these antibodies to ITIH2 by testing them on tissues known to express ITIH2 positively and negatively. Browse below to find the ITIH2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ITIH2 Infographic by Boster Bio

All ITIH2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cleaved-ITI-H2 (D702) Antibody

6 Q&As

Western Blot (WB) analysis of specific cells using Cleaved-ITI-H2 (D702) Polyclonal antibody

Human, Mouse, Rat

ELISA, WB

$399
Cat # A07196
100μl

Anti-ITI-H2 Antibody

Western blot (WB) analysis of ITI-H2 polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:Mouse brain tissue lysate
Lane3:Rat brain tissue lysate

Human, Mouse, Rat

$405
Cat # A07196-1
100ul

ITIH2 (NM_002216) Human Over-expression Lysate

Human

$960
Cat # LS003698
20 µg, 100 µg

ITIH2 Overview

Facts about Inter-alpha-trypsin inhibitor heavy chain H2.

ITIH2 3D structure. Source: alphafold

Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2)

May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. .

Gene Information

Human
Gene Name:	ITIH2
Uniprot:	P19823
Entrez:	3698

Family

Belongs to:

ITIH family

Alternative Names

H2P; IGHEP2; Inter-Alpha (Globulin) Inhibitor H2; inter-alpha (globulin) inhibitor, H2 polypeptide; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor complex component II; inter-alpha-trypsin inhibitor heavy chain H2; Intin2; ITI Heavy Chain H2; ITIH2; ITI-H2; ITI-HC2; Serum-derived hyaluronan-associated protein; SHAP

Molecular Weight

Mass (kDA):
106.463 kDA

Genomic Context


Human

Location:	10p14
Sequence:	10; NC_000010.11 (7703316..7749520)

Tissue Specificity

Plasma.

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Colonic Neoplasms
Endometrial Neoplasms
Glaucoma, Open-angle
Swine Diseases
Endometrial Polyp
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinogenesis
Carcinoma
Carcinoma In Situ
Neoplasms

Headache
Mammary Neoplasms
Retinal Diseases
Primary Open Angle Glaucoma
Diabetic Retinopathy
Lung Neoplasms
Glaucoma

Pathways

Ovulation
Pathogenesis
Localization

PTMs

Disulfide bond
Gamma-carboxyglutamic acid

Glycoprotein
Phosphoprotein

Proteoglycan

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITIH2

References

PMID: 2450046 by Gebhard W., et al. Complementary DNA and derived amino acid sequence of the precursor of one of the three protein components of the inter-alpha-trypsin inhibitor complex.

PMID: 2446322 by Salier J.-P., et al. Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.