Iodotyrosine deiodinase 1 Antibodies

AND Iyd ELISA kits, Iodotyrosine deiodinase 1 Proteins

Many biological assays use antibodies to detect Iodotyrosine deiodinase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Iodotyrosine deiodinase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Iodotyrosine deiodinase 1 antibodies...

We validate the specificity of these antibodies to Iodotyrosine deiodinase 1 by testing them on tissues known to express Iyd positively and negatively. Browse below to find the Iyd antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Iyd Infographic by Boster Bio

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Human IYD Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ6PHW0
Starting from 20ug

Iyd Overview

Facts about Iodotyrosine deiodinase 1.

Iodotyrosine deiodinase 1 (Iyd)

Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT) (PubMed:22238141). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways.

Acts more efficiently on monoiodotyrosine than on diiodotyrosine (By similarity). .

Gene Information

Mouse
Gene Name:	Iyd
Uniprot:	Q9DCX8
Entrez:	70337

Family

Belongs to:

nitroreductase family

Alternative Names

C6orf71; DEHAL1chromosome 6 open reading frame 71; dJ422F24.1; iodotyrosine dehalogenase 1; iodotyrosine deiodinase; IYD-1; TDH4

Molecular Weight

Mass (kDA):
32.814 kDA

Genomic Context


Mouse

Location:	10\|10 A1
Sequence:	10;

Diseases

Congenital Hypothyroidism
Goiter
Hypothyroidism
Thyroid Diseases
Thyrotoxicosis
Primary Hypothyroidism
Iodotyrosine Deiodination Defect

Croup
Sore To Touch

Pathways

Methylation
Dna Methylation
Excretion

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Iyd

References

PMID: 19436071 by Thomas S.R., et al. Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.

PMID: 22238141 by Buss J.M., et al. Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus.