Interferon-activable protein 202 (Ifi202)

Inhibits the transcriptional activity of several transcription factors, such as NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53.

Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity.