Igsf5 Antibodies

AND Igsf5 ELISA kits, Igsf5 Proteins

Many biological assays use antibodies to detect Igsf5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Igsf5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Igsf5 antibodies...

We validate the specificity of these antibodies to Igsf5 by testing them on tissues known to express Igsf5 positively and negatively. Browse below to find the Igsf5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Igsf5 Infographic by Boster Bio

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Igsf5 Overview

Facts about Immunoglobulin superfamily member 5.

Immunoglobulin superfamily member 5 (Igsf5)

Provides, together with MAGI1, an adhesion machinery at tight junctions, which might modulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion.

In testis, it might function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia- spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells- Sertoli cells.

Gene Information

Mouse
Gene Name:	Igsf5
Uniprot:	Q7TSN7
Entrez:	72058

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

GSF5; IGSF5; Immunoglobulin Superfamily 5 Like; Immunoglobulin Superfamily Member 5; Immunoglobulin Superfamily, Member 5; JAM4; JAM-4; JCAM; Junctional Adhesion Molecule 4; Putative Gene, Immunoglobulin Superfamily 5 Like11

Molecular Weight

Mass (kDA):
40.292 kDA

Genomic Context


Mouse

Location:	16\|16 C4
Sequence:	16;

Tissue Specificity

Localized to kidney glomeruli and small intestinal epithelial cells. In kidney glomeruli, it is localized at slit diaphragm. Also found in spermatogonia, gonocytes, hematopoietic stem cells and Sertoli cells.

Diseases

Tissue Adhesions

Pathways

Cell Adhesion
Germ Cell Development
Cell Development
Endocytosis
Rna Interference

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Igsf5

References

PMID: 12773569 by Hirabayashi S., et al. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1.

PMID: 16982697 by Nagamatsu G., et al. A CTX family cell adhesion molecule, JAM4, is expressed in stem cell and progenitor cell populations of both male germ cell and hematopoietic cell lineages.