Protein jagged-2 Antibodies

AND JAG2 ELISA kits, Protein jagged-2 Proteins

Many biological assays use antibodies to detect Protein jagged-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein jagged-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein jagged-2 antibodies...

We validate the specificity of these antibodies to Protein jagged-2 by testing them on tissues known to express JAG2 positively and negatively. Browse below to find the JAG2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Protein jagged-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the JAG2 Western Blot Guide

JAG2 Infographic by Boster Bio

All JAG2 Products

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Specificity

Applications

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Anti-Jagged 2/JAG2 Antibody Picoband®

Western blot analysis of Jagged 2/JAG2 using anti-Jagged 2/JAG2 antibody (A01428-1)

Human

ELISA, WB

$370
Cat # A01428-1
100 µg/vial

Anti-JAG2 Rabbit Monoclonal Antibody

Western blot analysis of JAG2 expression in HUVEC cell lysate

Human, Mouse

$370
Cat # M01428
100 μl/vial

JAG2 Overview

Facts about Protein jagged-2.

JAG2 3D structure. Source: alphafold

Protein jagged-2 (JAG2)

Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).

. .

Gene Information

Human
Gene Name:	JAG2
Uniprot:	Q9Y219
Entrez:	3714

Family

Belongs to:

No superfamily

Alternative Names

HJ2; JAG2; Jagged 2; Jagged2; protein jagged-2; SER2

Molecular Weight

Mass (kDA):
133.367 kDA

Genomic Context


Human

Location:	14q32.33
Sequence:	14; NC_000014.9 (105140981..105168776, complement)

Tissue Specificity

Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Cleft Palate
Carcinoma
Leukemia
Congenital Abnormality
Nervousness
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Stomach
Carcinogenesis
Hyperplasia
Neoplasm Metastasis

Tumor Angiogenesis
Tissue Adhesions
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Pancreas
Inflammation
Multiple Myeloma
Tumor Progression

Interacting Proteins

GFI1B

Pathways

Notch Signaling Pathway
Cell Differentiation
Cell Proliferation
Cell Development
Cell Fate Specification
Angiogenesis
Lateral Inhibition
Cell Fate Determination
Neurogenesis
Cell Cycle
Regeneration
Cell Growth
Hair Cell Differentiation

Secretion
Gliogenesis
Pathogenesis
Brain Development
Proteolysis
Localization
Cell Activation

PTMs

Cleavage
Phosphorylation

Glycosylation
Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/JAG2

References

PMID: 9315665 by Luo B., et al. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

PMID: 10079256 by Gray G.E., et al. Human ligands of the Notch receptor.