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- Table of Contents
KCNA3 Antibodies
AND KCNA3 ELISA kits, KCNA3 Proteins
Many biological assays use antibodies to detect KCNA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNA3 antibodies...
Designing a Western blot for KCNA3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KCNA3 Western Blot GuideKCNA3 Infographic by Boster Bio
All KCNA3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A03981Y187
100ul
Cat # A03981Y187
100ul
KCNA3 Overview
Facts about Potassium voltage-gated channel subfamily A member 3.
Potassium voltage-gated channel subfamily A member 3 (KCNA3)
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | KCNA3 |
| Uniprot: | P22001 |
| Entrez: | 3738 |
Family
| Belongs to: |
|---|
| potassium channel family |
Alternative Names
HGK5; HLK3KV1.3; HPCN3PCN3; HUKIII; Kv1.3; MK3; potassium channel 3; potassium voltage-gated channel subfamily A member 3; potassium voltage-gated channel, shaker-related subfamily, member 3; type n potassium channel; Voltage-gated K(+) channel HuKIII; voltage-gated potassium channel protein Kv1.3; Voltage-gated potassium channel subunit Kv1.3
Molecular Weight
Mass (kDA):
63.842 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.3 |
| Sequence: | 1; NC_000001.11 (110653560..110674940, complement) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Autoimmune Reaction
- Autoimmune Diseases
- Multiple Sclerosis
- Sclerosis
- Nervousness
- Decreased Immunologic Activity [pe]
- Experimental Autoimmune Encephalomyelitis
- Malignant Neoplasms
- Inflammation
- Encephalomyelitis
- Neoplasms
- Delayed Hypersensitivity
- Disease Of Adrenal Medulla
Interacting Proteins
- BAX
- DOLK
Pathways
- Localization
- Cell Activation
- T Cell Activation
- Cell Proliferation
- Pathogenesis
- Transport
- T Cell Proliferation
- Secretion
- Hypersensitivity
- Lymphocyte Proliferation
- Immune Response
- Glucose Homeostasis
- Cell Differentiation
PTMs
- Phosphorylation
- Carboxylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNA3
bosterbio.com/bosterbio-gene-info-cards/KCNA3
References
PMID: 7829094 by Folander K., et al. Confirmation of the assignment of the gene encoding Kv1.3, a voltage- gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1.
PMID: 1986382 by Philipson L.H., et al. Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.